LEVELS OF NEUROSPECIFIC ENOLASE AND ENOLASE-SPECIFIC AUTOANTIBODIES IN BLOOD SERUM OF THE PATIENTS WITH AUTOIMMUNE THYROPATIES

LEVELS OF NEUROSPECIFIC ENOLASE AND ENOLASE-SPECIFIC AUTOANTIBODIES IN BLOOD SERUM OF THE PATIENTS WITH AUTOIMMUNE THYROPATIES

The patients with autoimmune thyroiditis and various functional states of thyroid gland, and diffuse toxic goiter with pronounced thyrotoxicosis were studied for neurospecific enolase Mens Hats and enolase-specific autoantibodies levels in blood serum.Increased concentrations of neurospecific Books enolase and specific autoantibodies were revealed

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Software Reliability Growth Model Selection by Using VIKOR Method Based on q-Rung Orthopair Fuzzy Entropy and Divergence Measures

Car Screen Protectors Software reliability growth models (SRGMs) are widely used for predicting the reliability of software systems during testing and debugging.Selecting the most appropriate SRGM solutions is a multi-criteria decision-making (MCDM) problem that is very difficult when criteria are imprecise or ambiguous.The paper introduces a novel

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Computational investigations on target-site searching and recognition mechanisms by thymine DNA glycosylase during DNA repair process

DNA glycosylase, as one member of DNA repair machineries, plays an essential role in correcting mismatched/damaged DNA nucleotides by cleaving the N-glycosidic bond between the sugar and target nucleobase through the base excision repair (BER) pathways.Efficient corrections of these DNA lesions are critical for maintaining genome integrity and prev

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Multimodality analysis confers a prognostic benefit of a T-cell infiltrated tumor microenvironment and peripheral immune status in patients with melanoma

Background We previously reported results from a phase 1 study testing intratumoral recombinant poliovirus, lerapolturev, in 12 melanoma patients.All 12 patients received anti-PD-1 systemic therapy before lerapolturev, and 11 of these 12 patients also received anti-PD-1 after lerapolturev.In preclinical models lerapolturev induces intratumoral inna

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